Jardiance 25mg

Jardiance 25mg (Empagliflozin) Tablets

Overview

Jardiance 25mg contains Empagliflozin 25mg, a prescription medicine belonging to the sodium-glucose co-transporter 2 (SGLT2) inhibitor class. It is used in appropriate patients with Type 2 diabetes mellitus to improve blood glucose control. Empagliflozin also has established cardiovascular, heart-failure, and chronic-kidney-disease uses, although the appropriate indication and dose depend on the individual patient and local prescribing guidance.

Active Ingredient

Empagliflozin: 25mg per film-coated tablet

Medicine class: SGLT2 inhibitor
Drug form: Film-coated tablet
Route of administration: Oral

Mechanism of Action

The kidneys normally filter glucose from the blood and reabsorb much of it through a transporter called SGLT2. Empagliflozin blocks this transporter, reducing glucose reabsorption and increasing the amount of glucose eliminated through urine. This helps lower elevated blood glucose levels. Its effects on sodium handling and kidney function also contribute to its cardiovascular and renal benefits.

Uses

Jardiance may be prescribed, depending on the patient and approved local indications, to:

• Improve blood glucose control in Type 2 diabetes.

• Support diabetes management alongside diet and physical activity.

• Reduce certain cardiovascular risks in eligible patients with Type 2 diabetes and established cardiovascular disease.

• Treat eligible patients with heart failure.

• Help slow progression of chronic kidney disease in appropriate patients.

Jardiance is not a treatment for Type 1 diabetes.

Dosage and Administration

For glycaemic control, treatment commonly begins with empagliflozin 10mg once daily. In patients who tolerate treatment and require additional blood glucose control, a healthcare professional may increase the dose to 25mg once daily.

Jardiance can generally be taken once daily, with or without food. The 25mg strength should not automatically be used as a starting dose.

Dosage and suitability depend on the treatment objective, kidney function, other medicines, hydration status, and overall medical condition. Never increase, reduce, or stop treatment without professional advice.

Precautions

Before taking Jardiance, tell your healthcare professional if you:

• Have kidney or liver problems.

• Have Type 1 diabetes or a history of diabetic ketoacidosis.

• Have low blood pressure or are prone to dehydration.

• Take diuretics or other blood-pressure-lowering medicines.

• Frequently experience urinary or genital infections.

• Are fasting, acutely ill, or scheduled for surgery.

• Are pregnant, planning pregnancy, or breastfeeding.

• Take insulin or medicines that can cause hypoglycaemia.

Kidney function and hydration status may need assessment before and during treatment.

Important Warning: Diabetic Ketoacidosis

SGLT2 inhibitors can rarely cause diabetic ketoacidosis (DKA), a serious medical emergency. DKA can sometimes occur even when blood glucose is not extremely high.

Seek urgent medical attention for symptoms such as:

• Nausea or vomiting

• Abdominal pain

• Unusual tiredness

• Excessive thirst

• Difficulty or unusually rapid breathing

• Confusion

Temporary interruption may be required during certain illnesses, prolonged fasting, or around surgery according to medical advice.

Possible Side Effects

Common or clinically important side effects may include:

• Genital fungal infections or thrush

• Increased urination

• Urinary tract infection

• Thirst

• Dehydration

• Dizziness or low blood pressure

Hypoglycaemia is more likely when empagliflozin is combined with insulin or medicines such as sulfonylureas.

Rare but serious complications can include:

• Diabetic ketoacidosis

• Severe urinary infection

• Severe dehydration

• Serious allergic reactions

• Fournier's gangrene, a rare but serious infection affecting the genital or perineal area

Seek immediate medical care for severe or rapidly worsening symptoms.

Drug Interactions

Tell your healthcare professional about all medicines, supplements, and herbal products you use. Particular attention may be needed with:

• Insulin

• Sulfonylureas and other glucose-lowering medicines

• Diuretics

• Blood-pressure-lowering medicines

Treatment adjustments may be required to reduce the risk of hypoglycaemia, dehydration, or low blood pressure.

Pregnancy and Breastfeeding

Empagliflozin is generally not recommended during pregnancy, and treatment should be reviewed if pregnancy is planned or confirmed. It is also usually avoided during breastfeeding unless a healthcare professional determines otherwise.

Storage

Store according to the instructions on the original packaging. Keep the tablets protected from inappropriate heat and moisture and out of the sight and reach of children.

Frequently Asked Questions

1. What is Jardiance 25mg?
It is a prescription tablet containing 25mg of empagliflozin.

2. What is Jardiance primarily used for?
It is used for Type 2 diabetes and, in appropriate patients, certain heart-failure, cardiovascular, and chronic-kidney-disease indications.

3. How does empagliflozin work?
It blocks SGLT2 in the kidneys, increasing urinary glucose excretion.

4. Is Jardiance 25mg usually the starting dose?
Not generally for glycaemic control. Treatment commonly starts at 10mg once daily, with an increase to 25mg when appropriate.

5. Can Jardiance be taken with food?
It can generally be taken with or without food.

6. Is Jardiance insulin?
No. Empagliflozin is an oral SGLT2 inhibitor.

7. Can Jardiance be used with metformin?
Yes, the medicines may be prescribed together when clinically appropriate.

8. Can Jardiance be used with insulin?
Yes, but the risk of hypoglycaemia may increase and treatment may require adjustment.

9. Does Jardiance cause low blood sugar?
Used alone, the risk is relatively low. The risk increases when combined with insulin or certain other diabetes medicines.

10. Does Jardiance increase urination?
It can, because additional glucose is removed through urine.

11. Can Jardiance cause dehydration?
Yes. Increased urination can contribute to fluid loss in susceptible individuals.

12. Can Jardiance cause genital infections?
Yes. Genital fungal infections are a recognised side effect.

13. What is the most important serious warning?
Diabetic ketoacidosis is an important potentially life-threatening complication requiring urgent medical assessment.

14. Can people with kidney disease take Jardiance?
Suitability depends on kidney function and the reason for treatment. A healthcare professional must assess this individually.

15. Is Jardiance used for Type 1 diabetes?
No. It is not recommended for treating Type 1 diabetes because of the increased risk of ketoacidosis.

16. What happens if I miss a dose?
Follow the instructions supplied with your medicine or ask your pharmacist or prescriber. Do not take extra medicine to compensate unless specifically instructed.

17. Should Jardiance be stopped before surgery?
Temporary interruption may be required before certain surgical procedures. Follow the instructions of the healthcare team managing your treatment.

18. Can Jardiance be taken during pregnancy?
It is generally not recommended during pregnancy. Treatment should be reviewed by a healthcare professional.

19. Can Jardiance help with heart failure?
Empagliflozin has approved heart-failure indications for appropriate patients. The correct treatment plan and dose require medical assessment.

20. Can Jardiance be used for chronic kidney disease?
Empagliflozin is used for CKD in eligible patients, but suitability depends on individual clinical factors and current prescribing guidance.

E-E-A-T Content Statement

Onlinemedicine4u.com provides educational medicine information developed using authoritative prescribing information, established clinical guidance, and recognised healthcare sources. Our editorial approach supports Experience, Expertise, Authoritativeness, and Trustworthiness (E-E-A-T) through clear sourcing, transparent updates, accurate distinction between educational information and medical advice, and periodic content review. Author or medical-review credentials should only be displayed when the named professional genuinely wrote or reviewed the content.

Disclaimer

This page is for general educational and informational purposes only and does not replace professional medical advice, diagnosis, or treatment. Jardiance 25mg (Empagliflozin) is a prescription medicine and should be used only under the direction of a qualified healthcare professional. The appropriate indication, dosage, kidney-function requirements, treatment duration, and monitoring vary between individuals. Never start, stop, or change treatment without medical guidance. Seek urgent medical care for suspected diabetic ketoacidosis, a severe allergic reaction, serious infection, or other severe symptoms.